24/10/2025

Exercise is also treatment: the power of exercise against cancer

When we think of clinical research, we often remember new medications. But science goes far beyond that and the Cura Project Institute is here precisely to expand this understanding, sharing information about the importance of clinical research and how it transforms people's lives.

Research is not restricted to drug tests: it can also investigate changes in habits, such as the practice of physical activity, diet, and well-being. And the results show that this care has an enormous impact on the quality of life and even the survival of people with cancer.

A recent example comes from the Challenge Trial, a Canadian study led by Dr. Christopher M. Booth, from Queen's University, which proved that supervised exercise can reduce the risk of colon cancer returning and increase the chance of living longer.

In other words: not only do medications save lives - movement, information, and lifestyle change are also part of the treatment.


How was the study done

  • Colon cancer patients who had already completed surgery and chemotherapy participated.
  • They were divided into two groups:
    • Control: they received only one booklet containing tips for healthy living and encouraging physical activity.
    • Supervised exercise: they received the same booklet, but they were also accompanied by a physical activity consultant for three years.

This follow-up helped patients plan goals, organize time, and gradually increase the frequency of exercises - such as walking, cycling, running, and swimming - while maintaining the practice over time.

What the study showed

The patients who participated in the structured exercise program:

  • They increased their physical fitness (walking and breathing capacity tests).
  • They improved the quality of life and the daily mood.
  • They had a 28% reduction in the risk of cancer recurrence.
  • They lived 37% longer.

In practical numbers:

  • For every 16 people who followed the program, 1 prevented the return of cancer.
  • For every 14, 1 life was saved.

Side effects:

There were no serious problems - just a slight increase in the risk of muscle injury, something common in those starting an exercise routine.

Conclusion

The study showed, in an unprecedented way, that supervised physical exercise should be part of the standard treatment for patients with colon cancer. For this benefit to reach everyone, it is essential that hospitals, professionals, and health systems offer structured physical activity programs as part of cancer care.

The Cura Project Institute reinforces the importance of disseminating this type of scientific evidence. After all, clinical research is also about quality of life — about understanding how different approaches, medication or behavioral, can help cancer patients live better and longer.

Check out the full study: Challenge Trial — Journal of Clinical Oncology

See other news

Explore the latest content on our Blog now and keep up to date with the main achievements of the Cura Project Institute.

Support cancer research efforts today

Donate or partner to make a difference.
Donate

Stay informed with our newsletter

Sign up for our newsletter to receive regular updates on research progress and news from the institute.